This module examines how the structure and dynamics of proteins explains their biological function. Includes concepts in protein folding, protein interactions/specificity and protein regulation. Protein production and rapid biophysical characterisation approaches will be studied that include techniques for studying protein interactions and the insights they give to biology. Biological systems that require large conformational changes and allostery including large complexes/machines will be introduced. Biological insights gained from structural techniques such as x-ray crystallography, cryoEM and protein bioinformatics as well as techniques that study the dynamics of proteins such as NMR and molecular dynamics will be taught. Throughout, students will evaluate the field of integrative structural biology and the extent different approaches and concepts are complementary to each other and help explain the structural basis of biological processes at the molecular level. The module will be taught through a combination of lectures and workshops and assessed by two assessments that involve data interpretation and application to the key concepts/techniques covered in the course.