We have a fully equipped laboratory for synthetic medicinal chemistry and the necessary hardware and software for molecular modelling, some of which employs the University of Liverpool’s high performance computing clusters. Our facilities also feature a microwave-assisted automated peptide synthesiser and a parallel peptide synthesiser capable of producing multiple peptides simultaneously.
Through our collaborators we have access to biological screening for malaria (Professor Steven Ward), tuberculosis (Professor Giancarlo Biagini), filiriasis (Professor Mark Taylor), vector biology (Dr Mark Paine, Professor Hilary Ranson and Dr Victoria Ingham), pancreatitis (Professor Robert Sutton), snake venom (Professor Nicholas Casewell), Cryptococcus neoformans (Professor William Hope), motor neurone disease (Professor Samar Hasnain, Dr Svetlana Antonyuk, and Dr Raheela Awais), breast cancer (Professor Philip Rudland), and bacterial strains (Professor Jo Fothergill, Dr Daniel Neil and Dr Adam Roberts). Through our collaborations with Professor Lu-Yun Lian we have access to a range of biophysical techniques including high field NMR spectrometers, X-ray crystallography, isothermal calorimetry and surface plasmon resonance.
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