Health & Wellbeing
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Laboratory facilities provide scope for cellular and
molecular level studies and extensive capabilities in
the area of articular cartilage and tendon/ligament
metabolism. We use these techniques to screen potential
structure-modifying agents, or as part of Phase IV studies
of licensed agents.
We have expertise in studying reactive oxygen species in
muscle and other tissues; our facilities include dedicated
Bruker e-scan Electron Paramagnetic Resonance
equipment and a Nikon Eclipse C1 Plus confocal system.
We also offer state-of-the-art Aurora equipment for
studies of whole muscle through to single fibre skeletal
muscle mechanics.
Biomechanics specialists undertake full body dynamic
modelling studies and use finite elements analysis
of musculoskeletal mechanics and foot-ground
inter-actions. Modern facilities for gait analysis include
static- and treadmill-based point force and pressure
measurement; these are integrated with equipment
to measure energy consumption, high-speed 3D
motion capture and videography, and wireless
electromyography.
Capabilities and facilities
•
Human and canine gait analysis
•
Advanced imaging for domestic animal species
(
canine, feline, equine) using MRI, CT, DEXA and
digital X-ray
•
Modelling cartilage and tendon metabolism –
in
vitro
models (cartilage, tendon and ligament) with a
range of molecular read-outs
•
Full body dynamic modelling.
Relevant centres and groups
•
MRC-Arthritis Research UK Centre for Integrated
Research into Musculoskeletal Ageing.
For further information
on all our specialist
centres, facilities and
laboratories
go to page
179
